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1 article(s) from Bombuwala, Karunananda

Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel

Karunananda Bombuwala,
Thomas Kinstle,
Vladimir Popik,
Sonal O. Uppal,
James B. Olesen,
Jose Viña and
Carol A. Heckman

Beilstein J. Org. Chem. 2006, 2, No. 13, doi:10.1186/1860-5397-2-13

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Scheme 1: Reagents and conditions for synthesis of N-glutaryl-deacetylcolchicine. The reagents used at each s...

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Scheme 2: Reagents and conditions for protection of paclitaxel and coupling to N-glutaryl-deacetylcolchicine ...

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Figure 1: Microtubule arrangement as visualized by immunofluorescence localization of β-tubulin. Cells were t...

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Figure 2: Projections of a VRO showing + ends localized by antibody against EB1 in a control cell. Cell was t...

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Figure 3: Projections of a VRO showing + ends localized by antibody against EB1 in colchitaxel-treated cell. ...

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Figure 4: Microtubule arrangement as visualized by immunofluorescence localization of β-tubulin. Cells were t...

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Published 30 Jun 2006

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